The Probiotic Space Mission

Navigating the Digestive Universe to Reach Your Gut
2025/05/21

Probiotics are essential allies for your gut—helping to maintain a balanced microbiome, supporting digestion, and strengthening the immune system. But what many people don’t realize is that these microscopic health warriors face a life-threatening journey the moment they are created. It’s not an easy ride—it’s a full-on space mission, filled with extreme obstacles and biological hazards, all before they can even start working inside your body. 

Pre-Launch Challenges: The Journey Starts Before Ingestion

The adventure for probiotics begins long before they’re consumed. From the manufacturing stage, these microorganisms are already up against serious threats.

Most probiotic strains are extremely sensitive to external conditions like heat, humidity, and oxidation. Even slight temperature increases—especially above 45°C—can destroy their viability. High humidity during storage or transit can also reduce their survival rate dramatically, meaning many probiotics lose their power before even reaching the consumer.

It’s like a spaceship that gets damaged before liftoff—no matter how advanced it is, it won’t complete its mission without strong protection.

Entering the Body: A Dangerous Journey Through the Digestive Galaxy

Once consumed, probiotics embark on a hazardous trip through the human digestive system. For them, this is nothing short of flying through hostile space. 

Stomach Acid (pH 1.5–3.5)

This acidic environment is like a deadly meteor storm. It breaks down the probiotic cell walls, making survival nearly impossible for unprotected strains. 

Bile Salt

Upon reaching the small intestine, probiotics face bile salts—a natural detergent produced by the liver that can disrupt their cell membranes and internal structure. 

Lysozymes and Digestive Enzymes

These enzymes are designed to break down invaders. Lysozymes, in particular, attack the bacterial cell wall, making it hard for probiotics to maintain their form and function. 

Temperature Fluctuations & Oxygen Exposure

The human body is a dynamic environment. Constant shifts in temperature and oxygen levels create added stress that can easily destabilize fragile probiotics.

Without the proper protection, most probiotics don’t survive long enough to reach the gut. They’re like astronauts without spacesuits—exposed and doomed before they ever land.

 

New Bellus Patented Technology: 5-Layer Protective Shield for Probiotic Survival


To overcome these barriers, New Bellus developed an innovative 5-Layer Embedding Technology, patented in Taiwan (Patent No. M646187). 

This advanced encapsulation system acts like a next-gen spacecraft—wrapping each probiotic in a sponge-like structure protecting probiotics from start to finish. 

🔍 The 5 Protective Layers:
  1. Durable Outer Layer
    Built with a sponge-like structure for mechanical stability and delayed release—ensuring high survivability and targeted delivery.
  2. Heat-Resistant Layer
    Shields the probiotic from high temperatures during production, storage, and body heat post-ingestion.
  3. Acid-Resistant Layer
    Defends against stomach acid, allowing the probiotic to safely pass through the stomach.
  4. Bile Salt-Resistant Layer
    Neutralizes the impact of bile salts, preventing cellular damage.
  5. Lysozyme-Resistant Layer
    Provides a physical barrier against enzyme attacks, preserving the cell wall.
   Backed by Scientific Imaging and Testing

   Using Scanning Electron Microscopy (SEM), we can visually confirm the difference:

  • Unprotected probiotics appear exposed and vulnerable  
  • Embedded probiotics are safely enclosed within a sponge-like barrier  

In-vitro tests further prove the effectiveness:

  • 92.52% survival rate in gastric acid
  • 94.98% survival rate in bile salt
  • 87.92% survival rate in combined acid-bile exposure

This means probiotics with New Bellus 5-layer embedding technology can successfully colonize the intestines and deliver full benefits—something many standard probiotics struggle to achieve.

​🚀 Tiny Heroes on a Big Mission

Though small, probiotics face a giant mission. At New Bellus, our goal is to give them the tools they need to survive that journey and reach your gut with full force. Thanks to our 5-layer patented technology, each probiotic capsule becomes a space-ready shuttle—engineered to endure the digestive cosmos and deliver optimal results.  

📌Want to learn more about our probiotic technologies, product applications, or partnership opportunities? Contact us today to explore how we can help your next innovation thrive.