When it comes to nutraceutical innovation, efficacy means little without safety—and at New Bellus, we take both seriously.
Our Hericium erinaceus (Lion’s Mane) mycelium HE12, cultivated through patented submerged fermentation technology, has undergone comprehensive safety evaluations to ensure peace of mind for our partners and end users alike.
🔍 Passed Safety Tests:
✔Bacterial Reverse Mutation Test (Ames test)
✔In Vitro Mammalian Cell Gene Mutation Test (Thymidine Kinase method)
✔Acute Oral Toxicity Test
✔90-Day Repeated Dose Oral Toxicity Study in Rats
✔Prenatal Development Toxicity Study
Both genetic toxicology studies—the Ames test and the in vitro gene mutation assay—confirmed that HE12 shows no mutagenic effects. Likewise, results from oral toxicity and prenatal studies verified that HE12 poses no toxicological concerns, even with long-term or developmental exposure.
💡 These results provide solid scientific assurance that our Hericium erinaceus mycelium is not only powerful in function, but also safe for use in dietary supplements, functional foods, and long-term formulations.
🔍 Interested in integrating HE12 into your next brain health or anti-aging product?
👉 Contact us for updates on product safety, research insights, and application support.